This CLE course will provide a broad overview regarding the wealth of opportunities that exist when thinking about investing in the cannabis industry, including breakdowns and industry overviews with current trends in mergers and acquisitions. This is followed by a discussion of regulatory and other key issues for U.S. investor clients including banking, 280E, and lack of research. The course continues with information about investing in cannabis abroad with a special focus on Canada and the positive movements happening there, post-legalization. In conclusion, instructors provide important insight into accounting and tax issues with recommendations for handling complex tax issues and 280E ending with information about accounting compliance practices.